Utilizing data from electronic medical records and health insurance claims, this study compares incident cardiovascular (CV) events among users of atenolol and metoprolol tartrate with hypertension. Atenolol is water-soluble medication while metoprolol tartrate is lipid-soluble and cleared out more slowly from the body.
Before taking atenolol oral tablet, inform your healthcare provider if you have asthma, lung problems, diabetes, severe allergies, thyroid disease (an overactive gland), or pheochromocytoma (an adrenal gland tumor that increases heart rate). Also inform them if pregnant or breast-feeding.
Atenolol Vs Metoprolol Tartrate
Effectiveness
Both atenolol and metoprolol are effective beta blockers in lowering blood pressure. But metoprolol has been shown to decrease risk for cardiovascular (CV) events like heart attacks and strokes more effectively than atenolol; indeed, metoprolol far outshines atenolol in one meta-analysis and other beta blockers like propranolol and oxprenolol.
Atenolol and metoprolol share similar pharmacologies, yet should not be interchanged. Both medications are cardioselective beta blockers affecting heart and blood vessels; metoprolol typically requires more frequent dosing due to its shorter half-life than atenolol and lipophilicity properties, meaning it dissolves more readily in fatty environments; atenolol is water soluble so is taken only once daily.
Metoprolol and atenolol, two first-line treatments for hypertension, have also been proven to significantly decrease heart failure risk. Atenolol has been shown to significantly reduce symptoms and hospitalizations for heart failure among chronic stable patients while metoprolol has been proven to decrease mortality rates among those living with heart failure.
Atenolol is more effective at preventing cardiac arrhythmias due to its selective alpha-adrenergic receptor blocking properties; thus enabling it to lower systolic blood pressure by directly inhibiting calcium channels in heart muscle fibers, while metoprolol has greater peripheral vasodilatory effects and has shown improved diastolic blood pressure levels.
Both atenolol and metoprolol are effective medications for lowering blood pressure; however, they should not be considered interchangeable. Metoprolol ER has been shown to significantly reduce heart failure symptoms, decrease risk from cardiovascular disease mortality rates and help to lower blood pressure; it may even serve as a backup treatment plan if first-line hypertension medications don’t seem to provide enough relief.
Atenolol and metoprolol ER both can be effective treatments for performance anxiety, but atenolol may be particularly useful at blocking the effects of adrenaline or epinephrine on the fight-or-flight response in your body.
This helps ensure you remain calm and focused during any speech, meeting, zoom call or exam; additionally it may prevent symptoms characteristic of performance anxiety such as sweating, elevated blood pressure or nausea from occurring.
Side effects
Atenolol and metoprolol are both prescribed to treat heart conditions such as coronary artery disease and heart failure, as well as to lower blood pressure (hypertension). Both medicines can also help manage other drugs that control hypertension such as angiotensin-converting enzyme inhibitors and diuretics to bring down hypertension levels further.
Metoprolol and atenolol have both been extensively examined to ascertain their effectiveness at lowering blood pressure. One study concluded that both medications significantly reduced cardiovascular events such as heart attack and stroke risk, with metoprolol tartrate being slightly more effective at doing so than atenolol.
Metoprolol and atenolol may cause side effects including fatigue and depression in older adults; these side effects should not be used as an excuse to stop taking these medications; your physician may suggest gradually decreasing your dosage in this instance.
Metoprolol and atenolol are cardioselective beta blockers, meaning they only impact beta 1 receptors in your heart. This differs from non-cardioselective beta blockers such as clonidine or diltiazem which may impact multiple types of beta receptors within your body.
Though both medications effectively treat heart conditions, they shouldn’t be seen as interchangeable. Metoprolol has a shorter half life than atenolol, so it should be taken more frequently; additionally it’s more likely to cross the blood brain barrier and cause sleep disruptions due to being lipophilic; atenolol is water soluble with a longer half-life; this allows it to take effect more gradually without needing as frequent doses.
Before taking atenolol while pregnant or breastfeeding, consult with your healthcare provider first. As this medication passes into breast milk and could harm an unborn baby.
Also, as this drug may lead to low blood sugar in certain people taking it; diabetic patients must monitor their levels carefully while on this medication. In addition, kidney issues could make it more difficult for the body to flush away atenolol from its system quickly.
Dosage
Atenolol comes as a tablet and can be taken either with or without food, usually twice per day; its dosage may be adjusted based on other health conditions you may be managing; usually starting out at a lower dose and gradually increasing over time.
Metoprolol extended release is another long-acting pill option and should only be taken once daily.
Metoprolol is an extremely effective medication used to treat high blood pressure (hypertension), angina, congestive heart failure, certain arrhythmias and certain neurologic conditions.
Additionally, this drug may help people who have diabetes by improving blood sugar control as well as decrease the chances of having a coronary attack or stroke.
Metoprolol should also be noted as it may interact with certain medications, including antibiotics and blood pressure drugs, and it may alter how some vitamins and herbs function. Therefore, it’s essential that you inform your healthcare provider of all of the medications taken by you–including vitamins and herbal remedies–as this could have serious adverse reactions.
Stopping abruptly could result in worse chest pain and/or an abrupt increase in your blood pressure, though if necessary your physician may prescribe gradually decreasing dosage levels to bring about the desired effects.
Atenolol can aggravate asthma and chronic obstructive pulmonary disease (COPD) when taken in larger amounts by blocking certain beta receptors found in breathing passages. Therefore, doctors who are treating such conditions should only prescribe small doses with close monitoring from atenolol to keep you safe.
If you are pregnant or breast-feeding, atenolol should not be taken.
This medication can cross the placenta and potentially harm a fetus; additionally it can pass into breast milk and harm nursing babies. Consult your physician before breastfeeding while on atenolol as this could reduce milk supply as well as cause problems with vision; your physician should conduct frequent eye exams while you take atenolol to detect visual disturbances such as blurry vision that require immediate medical attention. If this occurs please seek medical advice immediately.
Indications
Atenolol and metoprolol are cardioselective beta blockers used to lower heart rate, as well as treating hypertension (high blood pressure).
Both medications require a valid valid valid valid prescription from your healthcare provider, with Atenolol often prescribed immediately-release oral tablets to relieve angina pectoris symptoms caused by insufficient oxygen-rich blood flowing to chest cells; it’s commonly taken alongside other medication for coronary artery disease prevention, and effective against both stable angina as well as unstable angina which comes during exertion or stress; plus treating hypertension – great combo.
Metoprolol comes in both short-acting and extended-release tablets and is widely prescribed to treat hypertension and angina pectoris.
A single daily dose may be given or it can be incorporated into an overall treatment plan that includes angiotensin-converting enzyme inhibitors and diuretics for maximum effect. Off-label, Metoprolol may also be used to prevent migraines or control tremors.
Metoprolol’s pharmacology is similar to atenolol’s; however, there are a few distinctions. Metoprolol is lipophilic – meaning it dissolving more quickly in fatty environments – so should typically be taken with food.
Furthermore, its metabolism in the liver by way of CYP2D6 enzyme is extensive; individuals carrying poor metabolizer (PM) phenotype experience higher metoprolol concentrations and shorter elimination half-lives than extensive metabolizers (EM).
Both metoprolol and atenolol may cause serious side effects. If you experience severe adverse reactions, contact your healthcare provider immediately. Pregnant and breastfeeding women should discuss potential risks and benefits with their healthcare provider prior to beginning these medications.
Do not abruptly discontinue taking atenolol as this could increase your risk of severe angina or abnormal heart rhythms. Instead, your healthcare provider should gradually reduce your dosage over several weeks. You should inform them if having surgery as atenolol may reduce blood circulation during surgery procedures and interfere with certain surgical processes.
Taking other medications with atenolol may cause harmful interactions; such as certain antidepressants, clonidine diuretics SSRIs and MAOIs interact with atenolol so make sure to consult with them prior to doing so if taking multiple atenolol medications simultaneously can have harmful interactions; contact them before doing anything.
