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Doxycycline is one of several antibiotics healthcare providers prescribe to treat strep throat. Available both as pills and liquid, it should typically be taken for 10 days for maximum efficacy.
Take this medication at evenly spaced times each day for maximum effectiveness, even if symptoms resolve quickly. Take all prescribed doses until your entire course of treatment has been taken, even if symptoms subside within days or even hours of starting treatment.
Does Doxycycline Treat Strep?

Doxycycline is an effective treatment for strep throat, although it is not typically the first-line option. It belongs to a class of broad-spectrum tetracycline antibiotics that can combat certain strains of streptococcus bacteria.
When used to address streptococcal infections, doxycycline therapy should be continued for a minimum of 10 days.
Strep throat, caused by Streptococcal bacteria, manifests as symptoms like a sore throat, chills, fever, and swollen lymph nodes in the neck. Prompt antibiotic treatment is crucial to prevent severe heart and kidney complications.
The preferred drugs for combating strep throat are penicillin or amoxicillin, which should be taken for the full 10-day course even if symptoms subside. For individuals allergic to penicillin, erythromycin serves as an alternative solution.
Doxycycline, a versatile medication, holds a wide range of uses. It is effective in treating various bacterial infections including rare ones such as anthrax, cholera, and typhus fever.
Additionally, it proves beneficial in combatting acne and rosacea. Nonetheless, before initiating treatment for strep throat or any other condition, it’s essential to seek guidance from a healthcare professional for an accurate diagnosis and appropriate care plan.
What Is the Dosage of Doxycycline for Strep Throat
The dosage of doxycycline for strep throat can vary based on the severity of the infection and the age of the patient. Below are the recommended dosages, as per the studies:
Adults typically take 200 mg of oral doxycycline as the initial dose on their first day of treatment, with 100 mg administered every 12 hours. Afterward, a maintenance dose of 100 mg per day is recommended. For streptococcal infections, it is advised to continue therapy for a duration of 10 days.
Children weighing less than 45 kg require a dosage determined by their body weight, which should be assessed by a doctor. The typical prescription is 2.2 mg per kg of body weight per day, split into two doses over 60 days. In cases of streptococcal infections, the initial dosage is usually higher at 4.4 mg per kg on the first day, followed by a maintenance dose of 2.2 mg per kg thereafter.
It’s important to consider that these dosage recommendations serve as general guidelines. However, it’s crucial to acknowledge that individual circumstances may vary, thus necessitating a tailored approach. Consulting with a healthcare professional is always advisable for an accurate and personalized dosage recommendation in accordance with your specific needs.
Doxycycline can be used to treat anaplasmia phagocytophilum (formerly Ehrlichia equi), potomac horse fever, and leptospirosis in horses. Doxycycline may also help foals suffering from proliferative enteropathy caused by Lawsonia intracellularis or b-hemolytic streptococcal infection; its efficacy needs further research.

What Are the Side Effects of Doxycycline
Doxycycline, like any medication, can have side effects. However, not everyone experiences them. Let’s discuss some of the common and serious side effects associated with doxycycline.
– Stomach upset or vomiting
– Oral or vaginal thrush
– Rash or itching
– Nail changes
– Mild irritation of the esophagus
– Taste loss
– Ringing or persistent noise in the ears
– Headaches
– Nausea
– Vomiting
– Diarrhea
– Loss of appetite
– Mild skin rash or itching
– Darkened skin color
– Vaginal itching or discharge
Serious side effects include:
– Increased brain pressure (headache, blurred vision, vomiting)
– Severe blisters and bleeding in lips, eyes, mouth, nose, and genitals
– Severe skin reactions
– Difficulty or pain in swallowing
– Dizziness
– Fast heart rate
– Severe stomach pain, watery or bloody diarrhea
– Loss of appetite, upper stomach pain spreading to back, tiredness, nausea or vomiting, dark urine, jaundice
Seek immediate medical attention for serious side effects or consult a healthcare provider for concerning or persistent effects. Note individual responses may vary.
Precautions
Doxycycline and similar antibiotics may lead to Clostridium difficile-associated diarrhea, which may be severe and require hospital treatment. Even if symptoms disappear, taking all prescribed dosage will ensure that any infection does not resurface.
Patients should thoroughly wash their hands after coughing or sneezing, before and after eating, and before using the toilet in order to reduce the spread of bacteria infections such as Strep throat. People should avoid contact with anyone who is suspected of having this illness.
As this medication may lead to permanent teeth discoloration and bone growth inhibition, its use during pregnancy or with children should be strictly limited. Furthermore, taking Doxycycline with any tetracyclines increases the risk of serious side effects such as Stevens-Johnson syndrome; also interacts with lithium thus increasing seizures risk.
What Are the Alternatives to Doxycycline for Treating Strep Throat
When it comes to treating strep throat, there are various alternatives to the commonly used doxycycline. The optimal choices for this condition are penicillin or amoxicillin, both of which should be taken for a duration of 10 days even if symptoms alleviate.
In cases where individuals have an allergy to penicillin, erythromycin serves as a suitable substitute. There are also other antibiotics available that can effectively treat strep throat.
- Cephalosporins: Cefadroxil, cephalexin, cefuroxime
- Macrolides: Azithromycin, clarithromycin
- Clindamycin for penicillin-allergic individuals.
When selecting an antibiotic, it is essential to consider various factors. These factors include the severity of the infection, the age of the patient, and any allergies or medical conditions present. To ensure an accurate diagnosis and appropriate treatment plan for strep throat or any other condition, consulting with a healthcare professional is always highly recommended.