Table of contents
Peyronie’s disease usually resolves itself within 12 out of 100 cases without intervention; however, if symptoms become painful or interfere with sexual intimacy, treatment should be sought immediately.
Peyronie’s disease can be treated using various strategies, including oral medication, traction and vacuum devices, injections and shock wave therapy.
Most medical societies do not recommend oral medications in the chronic phase of Peyronie’s disease due to an absence of evidence proving effectiveness.
How to Cure Peyronie’s Disease Without Surgery

Peyronie’s disease, an inflammatory condition, induces penile scar tissue formation, leading to abnormal curvature, reduced size, discomfort, and erectile dysfunction. While surgery is the definitive solution, several non-surgical alternatives exist for Peyronie’s disease treatment.
Consider the following non-surgical options:
- Oral Medications: Pentoxifylline and colchicine are oral medications utilized for treatment. Their efficacy may be limited, accompanied by potential side effects.
- Injectable Medications: Collagenase clostridium histolyticum (Xiaflex) and verapamil are injectable medications to break down penile scar tissue. Multiple injections over several months might be required.
- Penile Traction Therapy: Applying a mechanical device for penile stretching over time enhances penile length. It’s a non-surgical treatment with proven results in some patients.
- Shockwave Therapy: Intense sound waves target penile scar tissue disintegration, but evidence supporting its efficacy remains limited.
It is essential to acknowledge that non-surgical treatments may not be effective for everyone. In certain cases, surgical intervention may become necessary. It is advisable to consult with a healthcare professional who can assess your individual situation and determine the most suitable treatment plan.
Acoustic Wave Therapy
Acoustic Wave Therapy (AWT) offers non-surgical solutions for individuals with Peyronie’s disease. AWT utilizes both traction and acoustic shockwave therapy to significantly improve your condition.
AWT uses focused shock waves to create micro-trauma in target areas, stimulating natural healing processes within your body.
This includes activating chemicals which dilate blood vessels, thus increasing blood flow within the penis; encouraging new tissue formation (e.g. fibroblasts which make up connective tissues such as tendons & fascia); as well as using acoustic shockwaves which release pain-killing chemicals and block pain signals from reaching your brain.
A handheld instrument emitting soundwaves directly to the target area of the penis is used during this procedure, lasting 20-25 minutes and emitting 2000 pulses each session. Studies have proven this technique twice as effective than Viagra without harmful side effects.
Penile Traction Devices
Penile traction devices offer non-surgical ways of treating Peyronie’s disease. These devices work by applying traction force directly onto the area affected by this condition and gradually lengthening it, often for several hours each day until desired results have been attained.
Quick Extender Pro is an extremely comfortable and effective penile stretcher suitable for all skin types. This device helps elongate the penis by decreasing atypical curvatures while adding length to an erection.
Other treatments for Peyronie’s disease may include injections to break down plaque and other substances, or shockwave therapy to increase blood flow.
Many individuals living with the disorder report loss of penile length along with pain when trying to achieve an erection; penile traction devices and other treatments may be useful in alleviating these symptoms – speak to a physician for more information and see if any may apply to you.

Injections
Injections may be beneficial for those diagnosed with Peyronie’s disease who exhibit an extreme penile curve or bend. Injected medication typically breaks down scar tissue and improves curvature; medications like Xiaflex and Verapamil are commonly prescribed as injections into plaques to decrease inflammation and break down scar tissue – these remedies also tend to work best on men with less calcified plaques.
Some injections should be given into the deltoid muscle, which has an excellent blood supply and assists with absorption of medications. Others are administered subcutaneously – just under the skin – which are more slowly absorbed but may damage tissues due to needle penetration.
Before receiving an injection, doctors must clean and cover the injection site with alcohol to reduce discomfort. An over-the-counter topical numbing cream may also help. Finally, sharps containers must be used when discarding used syringes and needles since placing these items directly into regular trash can be hazardous.
Shockwave Therapy
Shockwave therapy uses electromagnetic pulses of energy to send electromagnetic pulses directly into the body in order to promote healing and alleviate discomfort. As it doesn’t require incisions or lengthy recovery times, shockwave therapy helps patients return more quickly to normal living.
Extracorporeal shock wave therapy (ESWT) involves practitioners using handheld devices that transmit soundwaves through the skin to treat affected areas. Ultrasound gel will typically be applied prior to beginning this form of treatment; typically lasting approximately four minutes with some soreness or discomfort experienced as your body works to heal it.
Peyronie’s disease is an uncomfortable condition that affects men of any age. There are various non-surgical treatment methods available to those diagnosed, including oral medications, traction devices and injections which can help manage symptoms of the condition and alleviate them. If left untreated it could worsen and make erectile function difficult or even impossible.
What Are the Risks and Benefits of Non-surgical Treatments for Peyronie’s Disease
Non-surgical remedies for Peyronie’s disease entail both risks and benefits. Here, we examine the associated risks and benefits:
Risks:
- Limited effectiveness: Not all individuals may respond favorably to non-surgical treatments, with reduced impact on penile curvature or symptom improvement.
- Side effects: Some non-surgical options, like oral medications and injectables, may trigger side effects. For instance, gastrointestinal discomfort with oral medications (e.g., pentoxifylline and colchicine) and pain or swelling at the injection site with collagenase clostridium histolyticum (Xiaflex) are possible.
- Unclear evidence: Due to limited research and inconsistent outcomes, the efficacy of several non-surgical treatments remains uncertain.
- Cost: Non-surgical interventions can be financially demanding, particularly when multiple sessions or treatments are necessary.
Benefits:
- Reduced deformity: Injectables and penile traction therapy may aid in reducing penile curvature and enhancing the penis’s appearance.
- Improved sexual function: Some non-surgical treatments have shown potential in enhancing sexual function for men with Peyronie’s disease.
- Stabilization of the disease: Non-surgical approaches can stabilize the condition, curbing further penile deformity progression, especially during the acute phase.
- Less invasive: Non-surgical treatments offer a preferred, less invasive alternative to surgery for certain individuals.
It is important to consider that the risks and benefits of non-surgical treatments can vary depending on the individual and the specific treatment. To ensure a well-informed decision, it is recommended to consult with a healthcare provider who will discuss the potential risks and benefits with you. Together, you can determine the most suitable treatment approach for your specific case.

How Effective Are Non-surgical Treatments for Peyronie’s Disease
The effectiveness of non-surgical treatments for Peyronie’s disease remains uncertain and can vary among different treatment approaches. Let’s delve into a summary that highlights the available information regarding the efficacy of these non-surgical treatments:
- Mechanical Traction Devices: Penile traction therapy exhibits some promise in reducing curvature and ameliorating symptoms. However, limited evidence necessitates further high-quality studies for conclusive determination.
- Intralesional Injections: Collagenase clostridium histolyticum (Xiaflex) and verapamil are used for intralesional injections to dissolve penile scar tissue. They demonstrate some effectiveness in reducing curvature and symptom improvement. Yet, outcomes may differ, warranting additional high-quality randomized controlled trials for establishing efficacy.
- Oral Medications: Pentoxifylline and colchicine are employed for Peyronie’s disease treatment. However, their effectiveness remains limited, with insufficient robust evidence supporting their use.
- Shockwave Therapy: Utilizing sound waves for scar tissue fragmentation has been explored for Peyronie’s disease treatment. Despite its potential, current evidence backing its efficacy is limited, and it is not widely recommended as a primary treatment option.
Notably, the existing evidence on non-surgical treatments for Peyronie’s disease is constrained, often drawn from small studies or case reports. Further research is necessary to ascertain their efficacy and identify optimal approaches.
Consultation with a healthcare provider is advised to discuss potential benefits and risks of non-surgical treatments and determine the most suitable treatment plan for your specific case.