Rheumatoid arthritis can cause painful swelling and stiffness in your joints, and also contribute to other problems.
Fatigue is a frequent side effect of arthritis (RA). It often appears suddenly and lasts for hours; sometimes even appearing prior to other RA symptoms like joint pain. Fatigue may even accompany low fever.
Unusual Symptoms of Rheumatoid Arthritis

Pain
RA can cause both pain and stiffness in joints such as hands, feet, knees, hips, shoulders and often displays itself symmetrically – that is to say on both sides of the body in an identical pattern.
Inflammation associated with RA can have far-reaching ramifications on other areas of the body, including skin, eyes, lungs and heart. These extra-articular symptoms are sometimes called flares and may come and go over time – more seriously impacting than joint swelling and tenderness alone.
Rheumatoid Arthritis can also cause rheumatoid nodules, firm, painless lumps that appear underneath the skin and are caused by fluid build-up in lymphatic system, part of immune system. They typically appear around elbow, toes and heels; however they may appear anywhere on body.
Furthermore, inflammation may lead to severe chest pain known as Pleurisy due to infection in lung lining (pneumonia), potentially life-threatening condition.
Stiffness
Though pain is the hallmark of RA, stiffness can also be an indicator. People living with the disease may wake up and find it hard to bend their joints, feeling awkward when making fists or opening doors – often on both sides of their bodies.
Early signs of RA can often present themselves in small joints, particularly the proximal interphalangeal (PIP) and metacarpophalangeal (MCP) joints in fingers, wrists, knees, ankles and shoulders. These joints often swell up with doughy or spongy swelling instead of firm, knobby enlargement seen with osteoarthritis.
RA can cause dry eyes, increasing the risk of another autoimmune condition called Sjogren’s syndrome that results in dry mouth, throat, nose, vagina and eyes. People living with RA are more likely to develop cataracts later in life and an increased risk of bone fractures.
All these issues can be treated using medicines like NSAIDs, corticosteroids or disease-modifying antirheumatic drugs that stop immune attacks against joints and tissues.
Fatigue
Fatigue is one of the hallmark symptoms associated with rheumatoid arthritis. While this symptom may not be widely discussed or recognized as indicative of this illness, its presence can have profound impacts on one’s quality of life.
As with other symptoms associated with RA, fatigue can fluctuate with severity depending on when flares arise and lessen when people enter remission. Furthermore, it may impact different parts of the body each time it strikes.
Sleep can help alleviate fatigue, though that is sometimes difficult with RA.
Other steps include healthy eating, regular exercise, stress reduction and smoking cessation – in particular methotrexate and leflunomide are effective treatments designed to slow an overactive immune system from damaging joints; newer biologic DMARD medications delivered as injections also aid joint preservation; antimalarial drug hydroxychloroquine (Plaquenil) may also provide some relief against fatigue.

Fever
Many people with rheumatoid arthritis (RA) experience low-grade fever. It may be one of the initial signs and acts as an early indicator that something may be amiss with their immune system, signaling it is time to seek medical help for their disease. Fever often subsides after other symptoms have been addressed; nevertheless it still makes up an essential piece of RA symptoms.
Fever is part of our body’s natural response to inflammation. It helps deliver additional fluid and cells directly into an affected area in order to protect it from further harm.
RA occurs when the immune system mistakenly attacks the lining of joints called synovium, leading to joint pain, swelling and possible damage.
People living with RA also often experience nonspecific systemic symptoms, such as fatigue and malaise.
These nonspecific systemic symptoms often outnumber joint-specific discomfort more quickly; fatigue is particularly prevalent. Over days or weeks, these systemic symptoms — specifically fatigue — come and go in cycles known as flares; it is essential to distinguish these from an acute infection or another illness which might produce feverishness.
Can These Unusual Symptoms Be the Only Symptoms of Rheumatoid Arthritis
Unusual symptoms of rheumatoid arthritis can manifest in different parts of the body. While they may not be common, individuals with rheumatoid arthritis may still experience them.
However, it’s important to note that these symptoms are not exhaustive and may not always be directly linked to the condition. The primary indicators of rheumatoid arthritis include joint pain, swelling, and stiffness.
Thus, seeking medical advice is imperative to determine the underlying cause of unfamiliar symptoms and explore suitable treatment options.
What Are Some Treatment Options for Rheumatoid Arthritis
Treatment options for rheumatoid arthritis can involve a combination of medications, lifestyle adjustments, and therapeutic approaches. Commonly used methods include the incorporation of medication regimens, modifications to daily habits and routines.
Medications: Disease-modifying antirheumatic drugs (DMARDs) are medications that slow down the progression of rheumatoid arthritis and help prevent joint damage. Examples of DMARDs include methotrexate, hydroxychloroquine, leflunomide, and sulfates.
Biologic response modifiers are medications that specifically target components of the immune system to effectively reduce inflammation. Examples of these medications include adalimumab, etanercept, and certolizumab.
Janus kinase (JAK) inhibitors are medications that hinder specific enzymes involved in the immune response. Prominent examples of such inhibitors include tofacitinib and baricitinib.
Physical and occupational therapy are essential for improving joint function, reducing pain, and increasing mobility. Physical therapy focuses on exercises and stretches, while occupational therapy addresses daily activities and employs joint protection techniques.
Weight-bearing exercise has numerous benefits. Engaging in regular activities like walking or swimming can strengthen muscles, improve joint flexibility, and effectively reduce pain.
Rest and joint protection are crucial for managing symptoms and preventing joint damage. By balancing periods of rest with appropriate activity, individuals can effectively minimize the impact on their joints. Additionally, utilizing assistive devices and adopting joint protection techniques can significantly reduce stress on the joints.
In severe cases where joint damage is significant, surgery may be recommended for improved mobility and pain reduction. Joint replacement surgery offers a potential solution in such situations.
When developing a personalized treatment plan, it is essential to collaborate closely with your healthcare team. This collaboration ensures that your unique needs and goals are effectively addressed.
How Can Physical Therapy Help Manage Rheumatoid Arthritis Symptoms

Physical therapy can play a significant role in managing the symptoms of rheumatoid arthritis. Here’s how physical therapy can help:
- Pain management: Physical therapists can use various techniques such as manual therapy, heat or cold therapy, and electrical stimulation to help alleviate pain associated with rheumatoid arthritis.
- Joint mobility and flexibility: Physical therapists can design exercise programs to improve joint mobility and flexibility. These exercises can help reduce stiffness, increase range of motion, and improve overall joint function.
- Strengthening muscles: Strengthening exercises prescribed by physical therapists can help improve muscle strength around the affected joints. Stronger muscles can provide better support to the joints and reduce the strain on them.
- Posture and body mechanics: Physical therapists can educate individuals with rheumatoid arthritis on proper posture and body mechanics to minimize stress on the joints during daily activities. This can help reduce pain and prevent further joint damage.
- Assistive devices: Physical therapists can recommend and teach the use of assistive devices such as braces, splints, or walking aids to support and protect the joints affected by rheumatoid arthritis.
- Education and self-management: Physical therapists can provide education on managing symptoms, conserving energy, and adapting daily activities to minimize joint stress. They can also teach self-management techniques to individuals with rheumatoid arthritis, empowering them to take an active role in their own care.
It’s important to consult with a physical therapist who specializes in rheumatoid arthritis to develop an individualized treatment plan that addresses your specific needs and goals.